B-vitamin and Mental Wellbeing: pilot clinical trialUpdated 2 months ago
What does the clinical study say about Vitals⁺?
Vitals⁺ isn’t just built on science—it’s backed by it. We conducted a pilot clinical trial to explore its impact on nutritional status and mental wellbeing in healthy volunteers.
🔬 What was the study?
A team of researchers from Heights and King’s College London conducted a study to test how daily Vitals⁺ affects key B-vitamin levels and mood in healthy adults.
Over 8 months, participants took Vitals⁺ daily. Before and after the intervention we measured:
B-vitamin blood biomarkers (how much of the nutrient is readily available in the body)
Mental wellbeing, using validated clinical questionnaires like the POMS, GHQ-12, and PSS
🤔 What did the study find?
Improved nutrient biomarker status:
Thiamine (B1), riboflavin (B2), folate (B9), and vitamin B12 levels significantly increased.
93% reached optimal Thiamine status, and 100% improved their Riboflavin levels to optimal. There was also a 43% improvement in Red Blood Cell Folate levels and a 43% increase in Serum B12 concentrations
Positive impact on mental wellbeing
Participants experienced significant reductions in: Fatigue, Confusion and Tension. There was also signs of a reduction in Psychological Distress.
🤔 Why does it matter?
These B-vitamins are essential for neurotransmitter production and energy metabolism—so topping them up can make a big difference in how you feel, especially in today’s nutrient-depleted world.
📚 Reference
Jarrett et al. (in press) The impact of a combined multivitamin and blueberry supplement on B- vitamin biomarker status and mental wellbeing in healthy adults: results from a pilot study. Proceedings of the Nutrition Society
Our Head of Science and Research, Dr Jarrett excitedly presented this Vitals+ data at the Nutrition Society Winter Conference in January 2025. The article is currently in press and can be found here.
The full trial data and write up can be located HERE