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Cerebiome®Updated 2 days ago

What is Cerebiome®—and why is it in Biotic⁺?


Cerebiome® is a clinically studied blend of probiotic strains that supports both gut health and mental wellbeing. It’s part of a growing field of “psychobiotics”—live bacteria that work through the gut-brain axis to help you feel calmer, more resilient, and emotionally balanced.

Included in Biotic⁺ at a clinically relevant dose, it contains:

  • Lactobacillus helveticus Rosell-52

  • Bifidobacterium longum Rosell-175

In human clinical trials this blend of strains has been shown to:

  • Reduce general stress levels by 44% (Messaoudi et al., 2010)

  • Support healthy mood, brain function, and emotional wellbeing

  • Improve gut comfort in times of stress (Diop et al., 2008)

  • Help regulate cortisol, the body’s stress hormone (Messaoudi et al., 2010)

  • Support serotonin and tryptophan pathways


🤔 What makes Cerebiome® unique?


Cerebiome® is a best-in-class probiotic with more than a decade of research and real-world use. It’s:

  • Clinically proven for stress and mood support

  • Made from live probiotic bacteria, with a well-established safety profile

  • Stable at room temperature—no refrigeration needed

  • Compliant with standards set by EFSA, WHO, FDA, and others


It’s included in Biotic⁺ for its unique ability to support both your gut and your mind—naturally, and without side effects.


🤔 How does Cerebiome® work?


It works through the microbiome-gut-brain axis—the communication link between your digestive system and your brain.

Cerebiome® helps to:

  • Promote a balanced gut microbiome

  • Strengthen the intestinal barrier

  • Support neurotransmitter regulation, like serotonin

  • Improve your response to stress—from the inside out


🔎 Want to learn more? Check out this short video


📚 References:


Diop et al. (2008). “Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial.” Nutrition Research 28(1): 1-5.


Messaoudi et al. (2011). Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. British Journal of Nutrition, 105(5), 755-764.


Kazemi, A., et al. (2018). “Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial.” Clinical Nutrition


Romijn, A. R., et al. (2017). “A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression.” Australian & New Zealand Journal of Psychiatry: 0004867416686694.


Wallace, C. J. K., & Milev, R. V. (2021). The Efficacy, Safety, and Tolerability of Probiotics on Depression: Clinical Results From an Open-Label Pilot Study. Frontiers in Psychiatry, 12.

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