Quatrefolic® Vitamin B9 (Folic Acid)Updated 2 days ago

Why does Vitals⁺ include Vitamin B9?

Vitamin B9—also known as folate or folic acid—is essential for normal blood formation, immune system support, and reducing tiredness and fatigue.

Vitals⁺ includes 500μg of folate, provided as 5-MTHF (Quatrefolic®)—a highly bioavailable, active form of folate that your body can use immediately. That’s 250% of your NRV, giving you strong daily support, especially when your diet or genetics might limit absorption of other forms.

🤔 What does Vitamin B9 actually do?

Folate supports fundamental processes across your whole body. It:

• Contributes to normal blood formation, helping prevent fatigue and low energy

• Supports the immune system, especially during periods of physical or mental stress

• Helps reduce tiredness and fatigue by supporting energy metabolism

• Supports DNA and RNA synthesis, essential for cell renewal and repair

It also works in close partnership with iron and Vitamin B12 to help protect against anaemia.

🤔 Why 5-MTHF (Quatrefolic®)?

Most supplements use folic acid, the synthetic form of B9. But not everyone can convert folic acid efficiently into its active form—especially people with a common MTHFR 677C/T gene variant. That’s why we use 5-MTHF (Quatrefolic®), the active and body-ready form of folate.

This means better absorption, more consistent results, and no build-up of unmetabolised folic acid in your system—something EFSA notes could raise concerns in high intakes of standard folic acid.

You can learn more about what sets Quatrefolic® apart here:

The EFSA’s scientific opinion on folate explains how folate supports red blood cell formation, brain health, and more, while their 2023 safety review explores safe upper limits for different folate forms—including 5-MTHF.